VPMI (Vital Probiotics Mutualism and Metabolism Ingredients) is an ecological biotechnology that creates the Green Red Bio Metabolome by enabling plant-derived probiotics to acquire genetic information from plant cells, become dominant strains, and metabolize plants into bioactive substances compatible with human cells. This technology, developed through global academic collaboration and clinical trials, supports theoretical research, core technology development, and industrialization models. The resulting bioactive substances can be used in bio-healthcare services and reformulated into diverse bio-products through purification and processing.